Entité de rattachement
UMR 7206 - Anthropologie Génétique (AGène)
Thème interdisciplinaire de recherche
Génétique des Populations - Modélisation
Recherches
Habilité(e) à diriger des recherches
Spécialité
Génétique des Populations

Responsabilités dans l'unité

Responsabilités hors unité

  • Muséum National d'Histoire Naturelle
  • Université Paris Cité
    • 2018-present

      Co-responsable du domaine d'enseignement "Bio-Informatique et Bio-Statistiques" (BIBS) de l'UFR Sciences du Vivant (SDV), Université Paris Cité

Présentation

Summary

2001-present 

Assistant Professor, Eco-Anthropologie (EA), Université Paris Cité, CNRS, Muséum national d’Histoire naturelle, Paris, France

2017 

Habilitation à Diriger des Recherches (HDR), Université Paris Diderot, Paris, France

1999-2001 

Postdoctoral researcher with Evelyne Heyer at Laboratoire Anthropologie Biologique, Musée de l’Homme, MNHN, Paris, France

1997-1999 

Teaching and Research Temporary Attaché (ATER), Université Paris-Sud 11, Orsay, France

1994-1998 

PhD thesis with Bernard Godelle and Pierre-Henri Gouyon at Laboratoire Ecologie, Systématique et Evolution, Université Paris-Sud 11, Orsay, France

1993-1994 

Scientifique du contingent at Laboratoire Bioénergétique, CEA, Saclay, France

1990-1993 

Institut National Agronomique Paris-Grignon (INA-PG - AgroParisTech), Paris, France

 

Teaching

  • Probability
  • Biostatistics
  • Population genetics, Population genomics
  • Molecular evolution
  • Molecular phylogeny
  • Programming: bash, R

 

Students

PhD Students

  • 2023-present: Charlotte Antoine (co-supervision with Florent Détroit, Romain Laurent)
  • 2012-2015: Elise A. Lucotte
  • 2010-2013: Romain Laurent (co-supervision with Raphaëlle Chaix)
  • 2008-2011: Jean-Tristan Brandenburg (co-supervision with Frédéric Austerlitz)

 

Software (Teaching)

 

Publications (2017-2022)

  • Guez J, Achaz G, Bienvenu F, Cury J, Toupance B, Heyer É, Jay F, Austerlitz F (2023) Cultural transmission of reproductive success impacts genomic diversity, coalescent tree topologies, and demographic inferences. Genetics 223: iyad007 - doi:10.1093/genetics/iyad007

     

  • Lucotte EA, Albiñana C, Laurent R, Bhérer C, Genome of the Netherland Consortium, Bataillon T*, Toupance B* (2022) Detection of sexually antagonistic transmission distortions in trio datasets. Evol-Lett 6: 203-2016 - doi:10.1002/evl3.271

     

  • Fortes-Lima CA, Laurent R, Thouzeau V, Toupance B, Verdu P (2021) Complex genetic admixture histories reconstructed with Approximate Bayesian Computation. Mol-Ecol-Resour 21: 1098-1117 - doi:10.1111/1755-0998.13325 - pmid:33452723

     

  • Chaix R, Ly G, Laurent R, Lafosse S, Toupance B, Monidarin C, Evrard O, Bourdier F, Pavard S (2020) Structures sociales et structures génétiques dans les populations humaines. Bull-Mem-Soc-Anthropol-Paris 32: 18-23 - doi:10.3166/bmsap-2020-0071

     

  • Ly G, Laurent R, Lafosse S, Monidarin C, Diffloth G, Bourdier F, Evrard O, Toupance B, Pavard S, Chaix R (2019) From matrimonial practices to genetic diversity in Southeast Asian populations: the signature of the matrilineal puzzle. Philos-Trans-R-Soc-Lond-B-Biol-Sci 374: 20180434 - doi:10.1098/rstb.2018.0434 - pmid:31303171

     

  • Dandine-Roulland C, Laurent R, Dall'Ara I, Toupance B, Chaix R (2019) Genomic evidence for MHC disassortative mating in humans. Proc-Biol-Sci 286: 20182664 - doi:10.1098/rspb.2018.2664 - pmid:30890093

     

  • Ly G, Alard B, Laurent R, Lafosse S, Toupance B, Monidarin C, Diffloth G, Bourdier F, Evrard O, Pavard S, Chaix R (2018) Residence rule flexibility and descent groups dynamics shape uniparental genetic diversities in South East Asia. Am-J-Phys-Anthropol 165: 480-491 - doi:10.1002/ajpa.23374 - pmid:29359511

     

Publications (1995-2016)

  • Lucotte EA, Laurent R, Heyer E, Ségurel L*, Toupance B* (2016) Detection of Allelic Frequency Differences between the Sexes in Humans: A Signature of Sexually Antagonistic Selection. Genome-Biol-Evol 8: 1489-1500 - doi:10.1093/gbe/evw090 - pmid:27189992

     

  • Heyer E, Brandenburg JT, Leonardi M, Toupance B, Balaresque P, Hegay T, Aldashev A, Austerlitz F (2015) Patrilineal populations show more male transmission of reproductive success than cognatic populations in Central Asia, which reduces their genetic diversity. Am-J-Phys-Anthropol 157: 537-543 - doi:10.1002/ajpa.22739 - pmid:25821184

     

  • Enaud L, Hadchouel A, Coulomb A, Berteloot L, Lacaille F, Boccon-Gibod L, Boulay V, Darcel F, Griese M, Linard M, Louha M, Renouil M, Rivière JP, Toupance B, Verkarre V, Delacourt C, de Blic J (2014) Pulmonary alveolar proteinosis in children on La Réunion Island: a new inherited disorder? Orphanet-J-Rare-Dis 9: 85 - doi:10.1186/1750-1172-9-85 - pmid:24927752

     

  • Ségurel L, Austerlitz F, Toupance B, Gautier M, Kelley JL, Pasquet P, Lonjou C, Georges M, Voisin S, Cruaud C, Couloux A, Hegay T, Aldashev A, Vitalis R, Heyer E (2013) Positive selection of protective variants for type 2 diabetes from the Neolithic onward: a case study in Central Asia. Eur-J-Hum-Genet 21: 1146-1151 - doi:10.1038/ejhg.2012.295 - pmid:23340510

     

  • Brandenburg JT, Austerlitz F*, Toupance B* (2012) Impact of fertility transmission and other sociodemographic factors on reproductive success and coalescent trees. Genet-Res-Camb 94: 121-131 - doi:10.1017/S0016672312000298 - pmid:22647505

     

  • Laurent R, Toupance B, Chaix R (2012) Non-random mate choice in humans: insights from a genome scan. Mol-Ecol 21: 587-596 - doi:10.1111/j.1365-294X.2011.05376.x - pmid:22121833

     

  • Manni F, Toupance B (2010) Autochthony and HLA Frequencies in the Netherlands: When Surnames are Useless Markers. Hum-Biol 82: 457-467 - doi:10.3378/027.082.0407 - pmid:21082912

     

  • Robert A, Toupance B, Tremblay M, Heyer E (2009) Impact of inbreeding on fertility in a pre-industrial population. Eur-J-Hum-Genet 17: 673-681 - doi:10.1038/ejhg.2008.237 - pmid:19092776

     

  • Manni F, Heeringa W, Toupance B, Nerbonne J (2008) Do surname differences mirror dialect variation? Hum-Biol 80: 41-64 - doi:10.3378/1534-6617(2008)80[41:DSDMDV]2.0.CO;2 - pmid:18505044

     

  • Gagnon A, Toupance B, Tremblay M, Beise J, Heyer E (2006) Transmission of migration propensity increases genetic divergence between populations. Am-J-Phys-Anthropol 129: 630-636 - doi:10.1002/ajpa.20330 - pmid:16342261

     

  • Yotova V, Labuda D, Zietkiewicz E, Gehl D, Lovell A, Lefebvre JF, Bourgeois S, Lemieux-Blanchard E, Labuda M, Vézina H, Houde L, Tremblay M, Toupance B, Heyer E, Hudson TJ, Laberge C (2005) Anatomy of a founder effect: myotonic dystrophy in Northeastern Quebec. Hum-Genet 117: 177-187 - doi:10.1007/s00439-005-1298-8 - pmid:15883838

     

  • Manni F, Toupance B, Sabbagh A, Heyer E (2005) New method for surname studies of ancient patrilineal population structures, and possible application to improvement of Y-chromosome sampling. Am-J-Phys-Anthropol 126: 214-228 - doi:10.1002/ajpa.10429 - pmid:15386234

     

  • Balaresque P, Toupance B, Quintana-Murci L, Crouau-Roy B, Heyer E (2004) Sex-specific selection on the human X chromosome? Genet-Res 83: 169-176 - doi:10.1017/S0016672304006858 - pmid:15462410

     

  • Balaresque P, Toupance B, Heyer E, Crouau-Roy B (2003) Evolutionary dynamics of duplicated microsatellites shared by sex chromosomes. J-Mol-Evol 57: S128-S137 - doi:10.1007/s00239-003-0018-z - pmid:15008409

     

  • Heyer E, Toupance B, Perri C, De Vito O, Foncin JF, Cecilia Bruni A (2003) Manic depressive illness in a founder population. Eur-J-Hum-Genet 11: 597-602 - doi:10.1038/sj.ejhg.5201001 - pmid:12891380

     

  • Gagnon A, Toupance B (2002) Testing isonymy with paternal and maternal lineages in the early Québec population: the impact of polyphyletism and demographic differentials. Am-J-Phys-Anthropol 117: 334-341 - doi:10.1002/ajpa.10059 - pmid:11920369

     

  • Le Thierry d'Ennequin M, Panaud O, Toupance B, Sarr A (2000) Assessment of genetic relationships between Setaria italica and its wild relative S. viridis using AFLP markers. Theor-Appl-Genet 100: 1061-1066 - doi:10.1007/s001220051387

     

  • Le Thierry d'Ennequin M*, Toupance B*, Robert T, Godelle B, Gouyon PH (1999) Plant domestication: a model for studying the selection of linkage. J-Evol-Biol 12: 1138-1147 - doi:10.1046/j.1420-9101.1999.00115.x

     

  • Tenaillon O*, Toupance B*, Le Nagard H, Taddei F, Godelle B (1999) Mutators, population size, adaptive landscape and the adaptation of asexual populations of bacteria. Genetics 152: 485-493 - pmid:10353893

     

  • Toupance B, Godelle B, Gouyon PH, Schächter F (1998) A model for antagonistic pleiotropic gene action for mortality and advanced age. Am-J-Hum-Genet 62: 1525-1534 - doi:10.1086/301865 - pmid:9585593

     

  • Taddei F, Radman M, Maynard-Smith J, Toupance B, Gouyon PH, Godelle B (1997) Role of mutator alleles in adaptive evolution. Nature 387: 700-702 - doi:10.1038/42696 - pmid:9192893

     

  • Leibl W, Toupance B, Breton J (1995) Photoelectric characterization of forward electron transfer to iron-sulfur centers in photosystem I. Biochemistry 34: 10237-10244 - doi:10.1021/bi00032a018 - pmid:7640279

     

Publications

2023
  • Guez Jérémy, Achaz Guillaume, Bienvenu François, Cury Jean, Toupance Bruno, Heyer Évelyne, Jay Flora & Austerlitz Frédéric, 2023Cultural transmission of reproductive success impacts genomic diversity, coalescent tree topologies, and demographic inferences. Cultural transmission of reproductive success has been observed in many human populations as well as other animals. Cultural… Genetics vol. 223, n° 4, iyad007 Type: Journal Article
    ISSN
    1943-2631
2022
  • Petit Ferdinand, Guez Jérémy, Pouyet Fanny, Heyer Evelyne, Toupance Bruno, Jay Flora & Austerlitz Frédéric, mars 2022Impact of Cultural Transmission of Reproductive Success on whole-genome data: simulation study and ABC inference. , , Poster
2020
  • CHAIX Raphaëlle, LY Goki, LAURENT Romain, LAFOSSE Sophie, TOUPANCE Bruno, Monidarin C., Evrard O., Bourdier F. and PAVARD Samuel, 2020Structures sociales et structures génétiques dans les populations humaines. BMSAP vol. 31, 1-2, p. 18-23
2019
  • LY Goki, LAURENT Romain, LAFOSSE Sophie, Monidarin Chou, Diffloth Gérard, Bourdier Frédéric, Evrard Olivier, TOUPANCE Bruno, PAVARD Samuel & CHAIX Raphaëlle, juillet 2019From Matrimonial Practices To Genetic Diversity in Southeast Asian Populations: The Signature Of The Matrilineal Puzzle. Philosophical Transactions of the Royal Society B: Biological Sciences vol. 374, n° 1780, p. 20180434
  • Dandine-Roulland Claire, LAURENT Romain, Dall’Ara Irene, TOUPANCE Bruno & CHAIX Raphaëlle, mars 2019Genomic Evidence for MHC Disassortative Mating in Humans. Proceedings of the Royal Society B: Biological Sciences vol. 286, n° 1899, p. 20182664
  • Dandine-Roulland C., Laurent R., Dall’Ara I., TOUPANCE Bruno, CHAIX Raphaëlle, 2019Genomic Evidence for MHC Disassortative Mating in Humans. Proceedings of the Royal Society B vol. 286, n° 20182664,
  • LY Goki, LAURENT Romain, LAFOSSE Sophie, Monidarin C., Diffloth G., Bourdier F., Evrard O., TOUPANCE Bruno, PAVARD Samuel & CHAIX Raphaëlle, 2019From matrimonial practices to genetic diversity in Southeast Asian populations: the signature of the matrilineal puzzle. Philos Trans R Soc Lond B Biol Sci vol. 374, n° 1780, p. 20180434
2018
  • LY Goki, ALARD Bérénice, LAURENT Romain, LAFOSSE Sophie, TOUPANCE Bruno, Monidarin C., Diffloth G., Bourdier F., Evrard O., PAVARD Samuel & CHAIX Raphaëlle, 2018Residence rule flexibility and descent groups dynamics shape uniparental genetic diversities in South East Asia. Am J Phys Anthropol vol. 165, n° 3, p. 480-491
2016
  • Lucotte Elise A, LAURENT Romain, HEYER Evelyne, SÉGUREL Laure and TOUPANCE Bruno, 2016Detection of Allelic Frequency Differences between the Sexes in Humans : a Signature of Sexually Antagonistic Selection. Genome Biology and Evolution vol. 8, n° 5, p. 1489-1500
2015
  • HEYER Evelyne, Brandenburg Jean-Tristan, Leonardi Michela, TOUPANCE Bruno, Balaresque Patricia, Hegay Tanya, Aldashev Almaz and AUSTERLITZ Frédéric, 2015Patrilineal Populations Show More Male Transmission of Reproductive Success Than Cognatic Populations in Central Asia, Which Reduces Their Genetic Diversity. American Journal of Physical Anthropology vol. 157, n° 4, p. 537-543